E-KAB-0580
Mouse IL-12 p40 Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0580
- Additional Names:
- IL12B,IL-12B,CLMF2,NKSF2,p40,IL-12/IL-23 p40
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Mouse
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- IL-12 p40
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P43432
- Synonyms:
- CLMF p40;cytotoxic lymphocyte maturation factor 40 kDa subunit;Il-1;Il-12;IL-12 p40 subunit;IL-12 subunit p40;Il-12b;Il-12p40;IL-23 subunit p40;Il12p40;interleukin-12 p40 subunit;interleukin-12 subunit beta;p40
- Extra Details:
- Cytokine that can act as a growth factor for activated T and NK cells , enhance the lytic activity of NK/lymphokine-activated killer cells , and stimulate the production of IFN-gamma by resting PBMC.Associates with IL23A to form the IL-23 interleukin , a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R , activates the Jak-Stat signaling cascade , stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- Shipping Conditions:
- Blue Ice