E-KAB-0571
Mouse RANK KappaL Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0571
- Additional Names:
- TNFSF11,TRANCE,RANKL,CD254,ODF,OPGL,OPTB2,hRANKL2,sOdf
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Mouse
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- RANκL
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- O35235
- Synonyms:
- Ly10;Ly109l;O;OD;ODF;OPG ligand;OPGL;osteoclast differentiation factor;osteoprotegerin ligand;R;RANKL;receptor activator of NF-kappaB ligand;receptor activator of nuclear factor kappa-B ligand;TNF-related activation-induced cytokine;Tra;Trance;tumor necrosis factor ligand superfamily member 11;tumor necrosis factor-related activation-induced cytokine
- Extra Details:
- Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor.Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells , chief among which is induction of long lasting oscillations in the intracellular concentration of Ca 2+ resulting in the activation of NFATC1 , which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts.
- Shipping Conditions:
- Blue Ice