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E-KAB-0568

Mouse IL-18 Antibody Pair Set

Size

£460.80

Was £512.00

SKU:
E-KAB-0568
Additional Names:
IL18,IGIF,IL-1g,IL-1F4,Interferon-gamma-inducing factor
Application:
ELISA
Physical State:
Other Biological Fluid, Plasma, Serum
Species Reactivity:
Mouse
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Reactivities:
Mouse
Buffer:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:
IL-18
Formulation:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Uniprot:
P70380
Synonyms:
IFN-gamma-inducing factor;Ig;Igif;Il-;IL-1 gamma;Il-18;interferon gamma-inducing factor;interleukin-1 gamma;interleukin-18
Extra Details:
Interleukin-18 ( L-18 ) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor , and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide ( LPS ) . After stimulation with IL-18 , natural killer ( NK ) cells and certain T cells release another important cytokine called interferon-G Gamma ( IFN-G Gamma ) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production , and enhance IgG2a production in B cells. IL-18 binding protein ( IL18BP ) can specifically interact with this cytokine , and thus negatively regulate its biological activity.
Shipping Conditions:
Blue Ice