Mouse TRAIL/TNFSF10 Antibody Pair Set

Size

£460.80

Was £512.00

SKU:: E-KAB-0562
Additional Names:: APO2L,Apo2-L,TL2,CD253
Application:: ELISA
Physical State:: Other Biological Fluid, Plasma, Serum
Species Reactivity:: Mouse
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Reactivities:: Mouse
Buffer:: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:: TRAIL/TNFSF10
Formulation:: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Uniprot:: P50592
Synonyms:: A330042I21Rik;AI448571;AP;APO-2L;Ly81;T;TL2;TNF-related apoptosis-inducing ligand;Tnlg6a;Trail;TRAIL/APO2L;tumor necrosis factor ligand 6a;tumor necrosis factor ligand superfamily member 10
Extra Details:: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain , but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis , and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines , which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.