E-KAB-0560
Mouse ACE Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0560
- Additional Names:
- ACE1,CD143,DCP,DCP1,ICH,MVCD3
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Mouse
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- ACE
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P09470
- Synonyms:
- angiotensin-converting enzyme;AW208573;CD143;dipeptidyl carboxypeptidase I;dipeptidyl peptidase;kininase II
- Extra Details:
- Dipeptidyl carboxypeptidase that removes dipeptides from the C-terminus of a variety of circulating hormones , such as angiotensin I , bradykinin or enkephalins , thereby playing a key role in the regulation of blood pressure , electrolyte homeostasis or synaptic plasticity.Composed of two similar catalytic domains , each possessing a functional active site , with different selectivity for substrates.Plays a major role in the angiotensin-renin system that regulates blood pressure and sodium retention by the kidney by converting angiotensin I to angiotensin II , resulting in an increase of the vasoconstrictor activity of angiotensin.Also able to inactivate bradykinin , a potent vasodilator , and therefore enhance the blood pressure response.Acts as a regulator of synaptic transmission by mediating cleavage of neuropeptide hormones , such as substance P , neurotensin or enkephalins.Catalyzes degradation of different enkephalin neuropeptides ( Met-enkephalin , Leu-enkephalin , Met-enkephalin-Arg-Phe and possibly Met-enkephalin-Arg-Gly-Leu ) .Acts as a regulator of synaptic plasticity in the nucleus accumbens of the brain by mediating cleavage of Met-enkephalin-Arg-Phe , a strong ligand of Mu-type opioid receptor OPRM1 , into Met-enkephalin.
- Shipping Conditions:
- Blue Ice