E-KAB-0543
Human AGT Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0543
- Additional Names:
- ANHU,SERPINA8
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- AGT
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P01019
- Synonyms:
- alpha-1 antiproteinase, antitrypsin;angiotensin I;angiotensin II;angiotensinogen;ANHU;fetal-liver predominant transporter 1;hFLT1;pre-angiotensinogen;serine (or cysteine) proteinase inhibitor;serpin A8;serpin peptidase inhibitor, clade A, member 8;SERPINA8
- Extra Details:
- The protein encoded by this gene , pre-angiotensinogen or angiotensinogen precursor , is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product , angiotensin I , is then cleaved by angiotensin converting enzyme ( ACE ) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension , and can cause renal tubular dysgenesis , a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation , and inflammatory bowel disease.
- Shipping Conditions:
- Blue Ice