E-KAB-0540
Human F7 Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0540
- Additional Names:
- FVII,Proconvertin,SPCA
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- F7
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P08709
- Synonyms:
- coagulation factor VII;coagulation factor VII (serum prothrombin conversion accelerator);eptacog alfa;FVII coagulation protein;proconvertin;Serum prothrombin conversion accelerator;SPCA
- Extra Details:
- This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form , and is converted to an active form by either factor IXa , factor Xa , factor XIIa , or thrombin by minor proteolysis. Upon activation of the factor VII , a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated , and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions , the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Shipping Conditions:
- Blue Ice