Human I-TAC/CXCL11 Antibody Pair Set

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£793.80

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SKU:: E-KAB-0536
Additional Names:: CXCL11,H174,IP-9,IP9,SCYB11,SCYB9B,b-R1
Application:: ELISA
Physical State:: Other Biological Fluid, Plasma, Serum
Species Reactivity:: Human
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Reactivities:: Human
Buffer:: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:: I-TAC/CXCL11
Formulation:: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Uniprot:: O14625
Synonyms:: b-R1;beta-R1;C-X-C motif chemokine 11;chemokine (C-X-C motif) ligand 11;H174;I-TAC;interferon gamma-inducible protein 9;interferon-inducible T-cell alpha chemoattractant;IP-9;IP9;SCYB11;SCYB9B;small inducible cytokine B11;small inducible cytokine subfamily B (Cys-X-Cys), member 11;small inducible cytokine subfamily B (Cys-X-Cys), member 9B;Small-inducible cytokine B11
Extra Details:: Chemokines are a group of small ( approximately 8 to 14 kD ) , mostly basic , structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane , G protein-coupled receptors. Chemokines also play fundamental roles in the development , homeostasis , and function of the immune system , and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies , CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene.

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