E-KAB-0492
Human CASP4 Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0492
- Additional Names:
- Caspase-4,CASP-4,ICE and Ced-3 homolog 2,ICH-2,ICE ( rel ) -II,Mih1,Protease TX,ICH2,TX
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- CASP4
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P49662
- Synonyms:
- apoptotic cysteine protease Mih1/TX;CASP-4;caspase 4, apoptosis-related cysteine peptidase;caspase 4, apoptosis-related cysteine protease;caspase-4;caspase-4 isoform alpha;ICE and Ced-3 homolog 2;ICE(rel)-II;ICE(rel)II;ICEREL-II;ICH-2;Mih1;Mih1/TX;protease ICH-2;protease TX;TX
- Extra Details:
- This gene encodes a member of the cysteine proteases that plays important roles in apoptosis , cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is ",caspase 4 , apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
- Shipping Conditions:
- Blue Ice