E-KAB-0483
Human IL-21 Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0483
- Additional Names:
- IL21,Za11
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- IL-21
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- Q9HBE4
- Synonyms:
- CVID11;IL-21;interleukin-21;Za11
- Extra Details:
- Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells.Implicated in the generation and maintenance of T follicular helper ( Tfh ) cells and the formation of germinal-centers. Together with IL6 , control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.May play a role in proliferation and maturation of natural killer ( NK ) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells.During T-cell mediated immune response may inhibit dendritic cells ( DC ) activation and maturation.
- Shipping Conditions:
- Blue Ice