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E-KAB-0470

Human IL-5 Antibody Pair Set

Size

£460.80

Was £512.00

SKU:
E-KAB-0470
Additional Names:
IL5,EDF,TRF,E-CSF,ESGF
Application:
ELISA
Physical State:
Other Biological Fluid, Plasma, Serum
Species Reactivity:
Human
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Reactivities:
Human
Buffer:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Immunogen:
IL-5
Formulation:
PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
Uniprot:
P05113
Synonyms:
B-cell differentiation factor I;colony-stimulating factor, eosinophil;EDF;eosinophil differentiation factor;IL-5;interleukin-5;T-cell replacing factor;TRF
Extra Details:
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation , maturation , recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor , which is a heterodimer , whose beta subunit is shared with the receptors for interleukine 3 ( IL3 ) and colony stimulating factor 2 ( CSF2/GM-CSF ) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 ( IL4 ) , interleukin 13 ( IL13 ) , and CSF2 . This gene , IL4 , and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Shipping Conditions:
Blue Ice