E-KAB-0463
Human PD-L1 Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0463
- Additional Names:
- CD274,B7-H1,PD-L1,PDCD1L1,PDL1,B7 homolog 1
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- PD-L1
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- Q9NZQ7
- Synonyms:
- B7 homolog 1;B7-H;B7H1;CD274 antigen;hPD-L1;PD-L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;programmed cell death 1 ligand 1
- Extra Details:
- Programmed cell death ligand 1 ( CD274,or B7-H1,PD-L1 ) ,is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors,the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell,and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal,essential for T-cell proliferation and production of IL10 and IFNG,in an IL2-dependent and a PDCD1-independent manner. PD-L1 is a 290 aa transmembrane protein with a calculated molecular weight of 33 kDa,the apparent molecular weight has been reported as 45-70 kDa,suggesting probable glycosylation .
- Shipping Conditions:
- Blue Ice