E-KAB-0447
Human AB Beta1-42 Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0447
- Additional Names:
- AB Beta ( 1-42 ),Amyloid Beta 42,Amyloid Beta 42
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- Aβ1-42
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P05067
- Synonyms:
- AAA;ABETA;ABPP;AD1;alpha-sAPP;alzheimer disease amyloid protein;amyloid beta (A4) precursor protein;amyloid beta A4 protein;amyloid precursor protein;amyloid-beta precursor protein;APPI;beta-amyloid peptide;beta-amyloid peptide(1-40);beta-amyloid peptide(1-42);beta-amyloid precursor protein;cerebral vascular amyloid peptide;CTFgamma;CVAP;peptidase nexin-II;PN-II;PN2;preA4;protease nexin-II;testicular tissue protein Li 2
- Extra Details:
- AB Beta derives from APP via proteolytic cleavage by proteases called A Alpha- , B Beta- and G Gamma-secretase. The A Alpha-secretase cleavage precludes the formation of AB Beta , while the B Beta- and G Gamma-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein ( APP ) , encoded by APP gene which locate on human chromosome 21q , is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth , neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain , kidney , heart and spleen , but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 ( AD1 ) . This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
- Shipping Conditions:
- Blue Ice