E-KAB-0426
Human FSTL3 Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0426
- Additional Names:
- FSTL3,FSRP,Follistatin-Related Protein,Follistatin Like 3,Follistatin-Like 3 ( Secreted Glycoprotein ),Follistatin-Related Protein 3
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- FSTL3
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- O95633
- Synonyms:
- FLRG;follistatin-like 3 (secreted glycoprotein);follistatin-like protein 3;follistatin-related gene protein;follistatin-related protein 3;FSRP
- Extra Details:
- Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family , such as activin , BMP2 and MSTN. Inhibits activin A- , activin B- , BMP2- and MSDT-induced cellular signaling , more effective on activin A than on activin B. Involved in bone formation , inhibits osteoclast differentiation. Involved in hematopoiesis , involved in differentiation of hemopoietic progenitor cells , increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
- Shipping Conditions:
- Blue Ice