E-KAB-0410
Human CFD Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0410
- Additional Names:
- ADN,Adipsin,DF,PFD,Factor D,Properdin Factor D Esterase
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- CFD
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P00746
- Synonyms:
- ADIPSIN;ADN;C3 convertase activator;complement factor D;complement factor D preproprotein;D component of complement (adipsin);DF;PFD;properdin factor D
- Extra Details:
- This gene encodes a member of the S1 , or chymotrypsin , family of serine peptidases. This protease catalyzes the cleavage of factor B , the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine , a cell signaling protein secreted by adipocytes , which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency , which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
- Shipping Conditions:
- Blue Ice