E-KAB-0379
Rat FAS/CD95 Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0379
- Additional Names:
- Apt1,Tnfrsf6,Fas,FAS,CD95
- Application:
- ELISA
- Species Reactivity:
- Rat
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Rat
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- FAS/CD95
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- Q63199
- Synonyms:
- apo-1 antigen;apoptosis-mediating surface antigen FAS;CD95 antigen;Fas (TNF receptor superfamily, member 6);Fas antigen (ATP1);Fas receptor;FASLG receptor;Tnfrsf6;tumor necrosis factor receptor superfamily member 6;Tumor necrosis factor receptor superfamily, member 6
- Extra Details:
- FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
- Shipping Conditions:
- Blue Ice