Mouse MMP-2 Antibody Pair Set

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£793.80

Was £882.00

SKU:: E-KAB-0313
Additional Names:: Mmp2
Application:: ELISA
Species Reactivity:: Mouse
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Reactivities:: Mouse
Buffer:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:: MMP-2
Formulation:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:: P33434
Synonyms:: 72 kDa gelatinase;72 kDa type IV collagenase;72kD gelatinase;72kD type IV collagenase;72kDa gelatinase;72kDa type IV collagenase;Clg;Clg4a;Ge;GelA;gelatinase A;matrix metalloproteinase 2;Matrix metalloproteinase-2;MMP-;MMP-2
Extra Details:: MMP2,also named as CLG4A,Gelatinase Am,TBE-1 and PEX,belongs to the peptidase M10A family. It is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature,angiogenesis,tissue repair,tumor invasion,inflammation,and atherosclerotic plaque rupture. MMP2 contributes to myocardial oxidative stress by regulating the activity of GSK3beta. It cleaves GSK3beta in vitro. MMP2 can be cleaved into PEX chain(~60kd).Western blot analysis showed that the 72 kDa and 62 kDa proteinase activities were pro-MMP2 and the active enzyme,respectively.