E-KAB-0296
Mouse TNFRSF1B Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0296
- Additional Names:
- Tnfr-2,Tnfr2,Tnfrsf1b
- Application:
- ELISA
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Mouse
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- TNFRSF1B
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P25119
- Synonyms:
- CD120b;p7;p75;p75 TNFR;p80 TNF-alpha receptor;TN;Tnf;TNF receptor beta chain;TNF-;TNF-a;TNF-alphaR2;TNF-R;TNF-R-II;TNF-R2;TNF-R75;TNF-RII;TNFal;TNFalpha-R2;TNFBR;TNFR;Tnfr-1;TNFR-II;Tnfr2;TNFR80;TNFRII;tumor necrosis factor receptor 2;tumor necrosis factor receptor superfamily member 1B;tumor necrosis factor receptor type II
- Extra Details:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
- Shipping Conditions:
- Blue Ice