Human CYFRA21-1 Antibody Pair Set

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£460.80

Was £512.00

SKU:: E-KAB-0282
Additional Names:: CK19,K19,K1CS,KRT19
Application:: ELISA
Species Reactivity:: Human
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Reactivities:: Human
Buffer:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:: CYFRA21-1
Formulation:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:: P08727
Synonyms:: 40-kDa keratin intermediate filament;CK-19;CK19;cytokeratin 19;Cytokeratin-19;K19;K1CS;keratin 19, type I;Keratin-19;keratin, type I cytoskeletal 19;keratin, type I, 40-kd
Extra Details:: The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19,one of type I keratins,is specifically expressed in the periderm,the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity,KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes,peripheral blood,and bone marrow of breast cancer patients. This antibody,generated against full length KRT19 protein,also recognizes KRT17,another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.