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E-KAB-0252

Human IGF2R Antibody Pair Set

Size

£460.80

Was £512.00

SKU:
E-KAB-0252
Additional Names:
IGF2R,CD222,CI-M6PR,CIMPR,M6P-R,M6P/IGF2R,MPR 300,MPR1,MPR300,MPRI
Application:
ELISA
Species Reactivity:
Human
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Reactivities:
Human
Buffer:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:
IGF2R
Formulation:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:
P11717
Synonyms:
300 kDa mannose 6-phosphate receptor;cation-independent mannose-6-phosphate receptor;CD222;CI Man-6-P receptor;CI-M6PR;CIMPR;IGF-II receptor;Insulin-like growth factor 2 receptor;insulin-like growth factor II receptor;M6P-R;M6P/IGF2 receptor;M6P/IGF2R;MPR 300;MPR1;MPR300;MPRI
Extra Details:
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
Shipping Conditions:
Blue Ice