E-KAB-0249
Human ON Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0249
- Additional Names:
- SPARC,BM-40,OI17,Osteonectin,acidic,cysteine-rich,Basement-membrane protein 40,Oncysteine-rich protein,Secreted protein acidic and rich in cysteine,secreted protein,ON
- Application:
- ELISA
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- ON
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P09486
- Synonyms:
- basement-membrane protein 40;BM-40;OI17;ON;ONT;Osteonectin;Secreted protein acidic and rich in cysteine;secreted protein, acidic, cysteine-rich (osteonectin);SPARC
- Extra Details:
- SPARC,also known as ON (Osteonectin) or BM-40 (Basement-membrane protein 40),is an extracellular glycoprotein with the calculated molecular mass of 35 kDa and the apparent molecular mass of 40-43 kDa and 50 kDa . SPARC belongs to a group of matricellular proteins defined as secreted components that do not contribute directly to the formation of structural elements but serve to modulate cell-matrix interactions and cellular functions . SPARC is expressed at high levels in bone tissue,is distributed widely in many other tissues and cell types,and is associated generally with tissues undergoing morphogenesis,remodeling and wound repair . It elicits changes in cell shape,inhibits cell-cycle progression,and influences the synthesis of extracellular matrix . Altered expression of SPARC has been reported in a variety of cancers,which include breast,ovarian,colorectal,and pancreatic cancer as well as melanoma and glioblastomas .
- Shipping Conditions:
- Blue Ice