Human PR3 Antibody Pair Set

Size

£793.80

Was £882.00

SKU:: E-KAB-0248
Additional Names:: AGP7,C-ANCA,CANCA,NP-4,NP4,P29,PR-3,PR3,PRTN3,Myeloblastin,C-ANCA antigen,Leukocyte proteinase 3,Neutrophil proteinase 4,Wegener autoantigen
Application:: ELISA
Species Reactivity:: Human
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Reactivities:: Human
Buffer:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:: PR3
Formulation:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:: P24158
Synonyms:: ACPA;AGP7;azurophil granule protein 7;C-ANCA;C-ANCA antigen;CANCA;leukocyte proteinase 3;MBN;MBT;myeloblastin;neutrophil proteinase 4;NP-4;NP4;P29;PR-3;PR3;serine proteinase, neutrophil;wegener autoantigen;Wegener granulomatosis autoantigen
Extra Details:: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.