E-KAB-0160
Human PINP Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0160
- Additional Names:
- COL1A1,EDSC,OI1,OI2,OI3,OI4,PINP,PICP,COL1,CTXI,COL1A Alpha1,Cross Linked C-telopeptide of Type I Collagen,Cross Linked N-telopeptide of Type I Collagen,Procollagen I C-Terminal Propeptide,Collagen alpha-1(I) chain,NTX I,Alpha-1 type I collagen
- Application:
- ELISA
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- PⅠNP
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P02452
- Synonyms:
- alpha-1 type I collagen;alpha1(I) procollagen;CAFYD;collagen alpha 1 chain type I;collagen alpha-1(I) chain;collagen alpha-1(I) chain preproprotein;collagen of skin, tendon and bone, alpha-1 chain;collagen, type I, alpha 1;EDSARTH1;EDSC;OI1;OI2;OI3;OI4;pro-alpha-1 collagen type 1;type I proalpha 1;type I procollagen alpha 1 chain
- Extra Details:
- Type I collagen is the most abundant structural protein of connective tissues such as skin,bone and tendon. It is synthesized as a procollagen molecule which is characterized by a 300 nm triple helical domain flanked by globular N- and C-terminal propeptides (1). The triple helical domain contains Gly-Xaa-Yaa triplets where Xaa and Yaa are frequently proline and hydroxyproline,respectively. The non-helical propeptides are removed by procollagen N- and C-proteinase activities so that the mature triple helices can self-assemble into collagen fibrils that provide tensile strength to tissues (1). Type I collagen is a heterotrimer that consists of two alpha 1(I) chains and one alpha 2(I) chain,although homotrimers consisting of three identical alpha 1(I) chains have also been described (2). This recombinant mini pro-alpha 1(I) collagen consists of a shortened alpha 1(I) chain with following domain structure from N- to C-terminus: N-propeptide,N telopeptide,the 33 most N-terminal Gly-Xaa-Yaa repeats,the 33 most C-terminal Gly-Xaa-Yaa repeats,C-telopeptide and C-propeptide. The preparation contains a mixture of the full-length molecule,pN collagen I( alpha 1) and the C-terminal propeptide. This truncated pro-alpha 1(I) collagen is a substrate for procollagen N-proteinase and procollagen C-proteinase.
- Shipping Conditions:
- Blue Ice