Human RBP4 Antibody Pair Set

Size

£460.80

Was £512.00

SKU:: E-KAB-0114
Additional Names:: RBP4,MCOPCB10,RDCCAS,RET4,PRBP,RBP,Retinol-binding protein 4,Plasma retinol-binding protein,Cleaved into Plasma retinol-binding protein,Plasma retinol-binding protein 1-181,Plasma retinol-binding protein 1-179,Plasma retinol-binding protein(1-176),PRO2222
Application:: ELISA
Species Reactivity:: Human
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Reactivities:: Human
Buffer:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:: RBP4
Formulation:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:: P02753
Synonyms:: MCOPCB10;plasma retinol-binding protein;PRBP;RBP;RDCCAS;retinol binding protein 4, plasma;retinol-binding protein 4;retinol-binding protein 4, interstitial
Extra Details:: RBP4 (retinol-binding protein 4) is a carrier protein that transports vitamin A (retinol) from the liver to the peripheral tissues. Synthesized primarily by hepatocytes and adipocytes as a 21 kDa non-glycosylated protein,RBP4 is secreted into the circulation as a retinol-RBP4 complex. In plasma the RBP4-retinol complex is bound to transthyretin (TRR),which prevents prevent kidney filtration. Two truncated forms of RBP4,RBP4-L (truncated at Leu-183) and RBP4-LL (truncated at Leu-182 and Leu-183),exist by proteolytic process. RBP4-L and RBP4-LL,which do not bind TTR,are normally excreted into the urine but accumulate in the serum during renal failure. Urinary RBP4 has been reported as marker for glomerular disease. RBP4 also was identified as an adipokine that elevated in some insulin-resistant states. Measurement of serum RBP4 could be used to assess the risk of insulin resistance,type 2 diabetes,obesity,and cardiovascular disease. (18752671,16034410)

Shipping Conditions:: Blue Ice