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E-KAB-0103

Rat IL-18 Antibody Pair Set

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£793.80

Was £882.00

SKU:
E-KAB-0103
Additional Names:
Il18,Igif
Application:
ELISA
Species Reactivity:
Rat
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Reactivities:
Rat
Buffer:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:
IL-18
Formulation:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:
P97636
Synonyms:
IFN-gamma-inducing factor;IL-1 gamma;IL-18;interferon gamma-inducing factor;interleukin-1 gamma;interleukin-18
Extra Details:
Pro-inflammatory cytokine primarily involved in epithelial barrier repair,polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.Upon binding to IL18R1 and IL18RAP,forms a signaling ternary complex which activates NF-kappa-B,triggering synthesis of inflammatory mediators.Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
Shipping Conditions:
Blue Ice