E-KAB-0099
Rat ICAM-1/CD54 Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0099
- Additional Names:
- Icam1,CD54,intercellular adhesion molecule 1,Icam-1,ICAM-1,CD54
- Application:
- ELISA
- Species Reactivity:
- Rat
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Rat
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- ICAM-1/CD54
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- Q00238
- Synonyms:
- CD54;ICAM;ICAM-1;intercellular adhesion molecule 1
- Extra Details:
- ICAM-1 (intercellular adhesion molecule-1),also known as CD54,is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin,Fibrinogen,Hyaluronan,rhinoviruses,and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease,type 2 diabetes,organ transplant dysfunction,oxidant stress,increased abdominal fat mass,hypertension,liver disease,certain malignancies,and cerebral malaria.
- Shipping Conditions:
- Blue Ice