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E-KAB-0019

Human CTSB Antibody Pair Set

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£460.80

Was £512.00

SKU:
E-KAB-0019
Additional Names:
APPS,CPSB,Cathepsin B,CTSB,CathepsinB,CATB,Cathepsin B1,cysteine protease
Application:
ELISA
Species Reactivity:
Human
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Reactivities:
Human
Buffer:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:
CTSB
Formulation:
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:
P07858
Synonyms:
amyloid precursor protein secretase;APP secretase;APPS;cathepsin B;cathepsin B1;CPSB;cysteine protease;epididymis secretory sperm binding protein;RECEUP
Extra Details:
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
Shipping Conditions:
Blue Ice