E-KAB-0012
Human ApoB Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0012
- Additional Names:
- APOB,FLDB,LDLCQ4,apoB-100,apoB-48,ApoB48,ApoB100,Apolipoprotein B,Apo B-48,Apo B-100
- Application:
- ELISA
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- ApoB
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P04114
- Synonyms:
- apoB-100;apoB-48;apolipoprotein B (including Ag(x) antigen);apolipoprotein B-100;apolipoprotein B48;FCHL2;FLDB;LDLCQ4
- Extra Details:
- This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
- Shipping Conditions:
- Blue Ice