Rat IgG1 (Immunoglobulin G1) ELISA Kit

Size

£128.70

Was £143.00

SKU:: E-EL-R3076
Additional Names:: IGHG1
Application:: ELISA
Physical State:: Other Biological Fluid, Plasma, Serum
Species Reactivity:: Rat
Storage Conditions:: 2-8[o]C
Supplier:: Elabscience
Format:: Colorimetric method,ELISA,Competitive
Extra Details:: Rat IgG1 is a subclass of immunoglobulins (IgGs), which are large molecular proteins produced by the immune system. Structurally, IgG1 consists of four polypeptide chains: two heavy chains and two light chains, forming a Y-shaped molecule. The variable regions of IgG1 confer antigen specificity, while the constant regions mediate effector functions.IgG1 plays a pivotal role in humoral immunity, exhibiting high affinity for antigens and activating complement pathways. It is also involved in antibody-dependent cellular cytotoxicity (ADCC) and opsonization. In disease contexts, alterations in rat IgG1 levels can indicate immune dysfunction. For instance, elevated IgG1 levels may be observed in autoimmune disorders or infections.Moreover, IgG1 interacts with various factors, including Fc receptors on immune cells, which regulate its biological activities. The glycosylation pattern of IgG1 also influences its effector functions and therapeutic potential.In summary, rat IgG1 is a versatile immune molecule with a defined structure and diverse functions, playing a critical role in health and disease.