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E-EL-R3075

Rat REN (Renin) ELISA Kit

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£128.70

Was £143.00

SKU:
E-EL-R3075
Additional Names:
Angiotensinogenase,FLJ10761, HNFJ2, Prorenin, REN, renin precursor,renal, Renin
Application:
ELISA
Physical State:
Other Biological Fluid, Plasma, Serum
Species Reactivity:
Rat
Storage Conditions:
2-8[o]C
Supplier:
Elabscience
Format:
Colorimetric method,ELISA,Sandwich
Uniprot:
P08424
Synonyms:
angiotensinogenase;RATRENAA;Ren1;RENAA;renin;renin 1 structural
Extra Details:
Renin is a secreted endopeptidase that plays a crucial role in the regulation of blood pressure and salt balance through the cleavage of angiotensinogen,which is the only known physiological substrate of Renin. The 406 aa precursor includes a signal peptide (aa 1 - 23),a propeptide (aa 24 - 66),and a mature chain (aa 67 - 406). It is an aspartyl protease that cleaves angiotensinogen to form angiotensin I. Renal Renin (Renin-1) is synthesized as a 381 aa proform (aa 22 - 402). In the kidney,prorenin is proteolytically cleaved after Thr71 to generate a mature enzyme.
Shipping Conditions:
Blue Ice