E-EL-R0643
Rat AGER(Total Advanced Glycosylation End Product Specific Receptor) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-EL-R0643
- Additional Names:
- RAGE
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Rat
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- Q63495
- Synonyms:
- advanced glycosylation end product-specific receptor;advanced glycosylation end product-specific receptor variant 2;advanced glycosylation end product-specific receptor variant 3;advanced glycosylation end product-specific receptor variant 4;advanced glycosylation end product-specific receptor variant 5;RAGE;receptor for advanced glycosylation end products
- Extra Details:
- Receptor for advanced glycation end products or AGER is a multi-ligand receptor that belongs to the immunoglobulin superfamily of cell surface molecules. AGER can be found in adult lung and skin tissue but low levels are found in other tissue types such as endothelia, cardiomyocytes, neutrophils, macrophages, lymphocytes, dendritic cells, and the central nervous system. AGER activation induces a positive feedback response to AGER leading to increase in expression of AGER regardless of expression levels. AGER has been found to be involved in pathogenesis and complications that are age related such as diabetes and Alzheimer's, as well as being involved in cellular processes such as inflammation, apoptosis, autophagy, and proliferation.
- Shipping Conditions:
- Blue Ice