E-EL-M2432
Mouse FcE EpsilonRII/CD23(Receptor II for the Fc Region of Immunoglobulin E) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-EL-M2432
- Additional Names:
- FCER2,BLAST-2,CD23A,CLEC4J,FCE2,IGEBF,Fc epsilon RII,FcE EpsilonRII
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P20693
- Synonyms:
- CD23;FC epsilon RII;fc-epsilon-RII;Fce2;Fcer2;low affinity immunoglobulin epsilon Fc receptor;low-affinity IgE receptor;Ly-4;Ly-42;lymphocyte IgE receptor
- Extra Details:
- CD23 is a 45 kD protein, also known as Leu-20, FcE EpsilonRII, IgE Fc receptor, BLAST-2, B6, and low affinity IgE receptor. CD23 responds to high levels of IgE by downregulating IgE secretion. In human monocytes, CD23 triggering results in release of pro-inflammatory cytokines including TNF-A Alpha, IL-1, IL-6, and GM-CSF. CD23 can be proteolytically cleaved to generate soluble CD23 fragments of various molecular weights. In chronic lymphocytic leukemia, levels of soluble CD23 in the serum can be used as a prognostic marker to identify patients at high risk for disease progression.
- Shipping Conditions:
- Blue Ice