E-EL-M0529
Mouse GAL3(Galectin 3) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-EL-M0529
- Additional Names:
- LGALS3,CBP35,GALBP,GALIG,L31,LGALS2,MAC2,Lectin,Galactoside-Binding Soluble 3
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P16110
- Synonyms:
- 35 kDa lectin;carbohydrate-binding protein 35;CBP 35;ga;gal-3;gal3;galactose-specific lectin 3;galect;galectin-3;GBP;igE-binding protein;L-3;L-34;L-34 galactoside-binding lectin;laminin-binding protein;lectin L-29;Mac-;Mac-2;mac-2 antigen
- Extra Details:
- Galectin-3 is a member of the lectin family, which includes 15 mammalian lectin members. Like all galectins, galectin-3 contains a carbohydrate recognition binding domain of about 130 amino acids that enables the specific binding of B Beta-galactosides. This protein has been shown to be involved in cell adhesion, cell activation, chemoattraction, cell growth and differentiation, cell cycle, and apoptosis. Galectin-3 induces pro-inflammatory cytokines and inhibits Th2 type cytokine production. It chemoattracts monocytes and macrophages, and activates and degranulates basophils and mast cells. Galectin-3 has been shown to be involved in cancer, inflammation, fibrosis, heart disease, and stroke. It has also been shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, tissue repair, inflammation, fibrogenesis, and ventricular remodeling. In addition, galectin-3 was found to contribute to tumor cell evasion of the immune system. Galectin-3 is increasingly being used as a diagnostic marker for different cancers.
- Shipping Conditions:
- Blue Ice