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E-EL-H6294

Human FSTL3 (Follistatin Like Protein 3) ELISA Kit

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£128.70

Was £143.00

SKU:
E-EL-H6294
Additional Names:
FSTL3,FSRP,Follistatin-Related Protein,Follistatin Like 3,Follistatin-Like 3 (Secreted Glycoprotein),Follistatin-Related Protein 3
Application:
ELISA
Physical State:
Other Biological Fluid, Plasma, Serum
Species Reactivity:
Human
Storage Conditions:
2-8[o]C
Supplier:
Elabscience
Format:
Colorimetric method,ELISA,Sandwich
Uniprot:
O95633
Synonyms:
FLRG;follistatin-like 3 (secreted glycoprotein);follistatin-like protein 3;follistatin-related gene protein;follistatin-related protein 3;FSRP
Extra Details:
Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such as activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling, more effective on activin A than on activin B. Involved in bone formation, inhibits osteoclast differentiation. Involved in hematopoiesis, involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
Shipping Conditions:
Blue Ice