Neutrophil Elastase (NE) Activity Colorimetric Assay Kit

Size

£286.20

Was £318.00

SKU:: E-BC-K899-M
Physical State:: Tissue
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles. Protect from light.
Supplier:: Elabscience
Immunogen:: NE
Format:: Colorimetric
Extra Details:: Neutrophil Elastase (NE) is one of the main serine proteases secreted by neutrophils. It plays an important role in the physiological and pathological processes of the body, on the one hand NE participate in the formation of the body's defense system and assist in the elimination of pathogenic microorganisms. On the other hand, the excessive activation of NE, in the case of imbalance with endogenous inhibitors, is directly involved in tissue damage, and is closely related to the occurrence of a variety of inflammation-related diseases, such as atherosclerosis, chronic obstructive pulmonary disease, pulmonary cystic fibrosis and other diseases, which can be used as a prevention and treatment target for these diseases. The detection principle of this kit is as follows: NE hydrolyzates the substrate to generate chromogenicity substances, which have maximum absorption at the wavelength of 380 nm, and NE activity in the sample is calculated by measuring the OD value at 380 nm and the standard curve.