APC Anti-Mouse CD20 Antibody[SA271G2]

Size

£82.80

Was £92.00

SKU:: E-AB-F1403E
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD20
Clone:: SA271G2
Uniprot:: P19437
Synonyms:: AA960661;B-cell differentiation antigen Ly-44;B-lymphocyte antigen CD20;Cd20;CD20 antigen;Ly-4;Ly-44;lymphocyte antigen 44;Membrane-spanning 4-domains subfamily A member 1;membrane-spanning 4-domains, subfamily A, member 2;Ms4a2
Extra Details:: CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.