E-AB-F1392E
APC Anti-Human CD195/CCR5 Antibody[HEK/1/85a]
Size
£115.20
Was £128.00
- SKU:
- E-AB-F1392E
- Additional Names:
- CCR5,C-C chemokine receptor type 5,HIV-1 fusion co-receptor
- Application:
- Flow Cytometry
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- CD195
- Clone:
- HEK/1/85a
- Uniprot:
- P51681
- Synonyms:
- C-C chemokine receptor type 5;C-C motif chemokine receptor 5 A159A;CC-CKR-5;CCCKR5;CCR-5;CD195;chemokine (C-C motif) receptor 5;chemokine receptor CCR5;chemokine recptor CCR5 Delta32;chemr13;CKR-5;CKR5;CMKBR5;HIV-1 fusion coreceptor;IDDM22;mutant C-C motif chemokine receptor
- Extra Details:
- CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1A Alpha, MIP-1B Beta, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
- Shipping Conditions:
- Blue Ice