E-AB-F13720
Purified Anti-Human CD45 Antibody[BC8], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F13720
- Additional Names:
- B220,CD45,CD45R,GP180,L-CA,LCA,LY5,T200,PTPRC,CD45 antigen,CD45R0,Ly-5,protein tyrosine phosphatase,receptor type,Receptor-type tyrosine-protein phosphatase C,CD45RO,Receptor-type tyrosine-protein phosphatase CLeukocyte common antigen (L-CA), T200,c polypeptide,CD 45,homolog of,Leukocyte common antigen,loc,Lyt-4,OTTHUMP00000033813,OTTHUMP00000033816,OTTHUMP00000033817,OTTHUMP00000038574,Protein tyrosine phosphatase receptor type c polypeptide,protein tyrosine phosphatase,receptor
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Human CD45 protein
- Clone:
- BC8
- Uniprot:
- P08575
- Synonyms:
- B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;LY5;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
- Extra Details:
- CD45, previously called LCA (leukocyte common antigen), T200, or Ly5 in mice, is member C of the class 1 (receptor-like) protein tyrosine phosphatase family (PTPRC). It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin . Multiple splicing isoforms of exon 4 (A), 5 (B), and 6 (C) are expressed according to cell type, developmental stage and antigenic exposure . The longest form, CD45RABC (called B220 in mouse) is expressed on B lymphocytes, The shortest form, CD45R0, lacking exons 4, 5 and 6 which encode aa 34-194, is expressed on memory cells, while intermediate sizes are expressed on other T cells. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice