PE Anti-Human CD57 Antibody[HI57a]

Size

£103.50

Was £115.00

SKU:: E-AB-F1333D
Additional Names:: HNK-1,NK-1,Leu-7
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD57
Clone:: HI57a
Uniprot:: Q9P2W7
Synonyms:: Beta-1,3-glucuronyltransferase 1;CD57;galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1;GLCATP;GLCUATP;glucuronosyltransferase P;HNK1;LEU7;LEU7 antigen;NK-1;NK1;UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase
Extra Details:: CD57, also known as TB01, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).