FITC Anti-Human CD203c Antibody[NP4D6]

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£100.80

Was £112.00

SKU:: E-AB-F1297C
Additional Names:: ENPP3,E-NPP3,PD-Ibeta
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: PBS
Immunogen:: CD203c
Clone:: NP4D6
Uniprot:: O14638
Synonyms:: B10;CD203c;dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3);dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3);ectonucleotide pyrophosphatase/phosphodiesterase family member 3;gp130RB13-6;NPP3;PD-IBETA;PDNP3;Phosphodiesterase I beta;phosphodiesterase I/nucleotide pyrophosphatase 3;phosphodiesterase-I beta
Extra Details:: CD203c, a transmembrane protein and a member of the ectoenzyme family, is involved in the hydrolysis of extracellular oligonucleotides, nucleoside phosphates, and NAD (possesses ATPase and ATP pyrophosphatase activity). The molecular weight of CD203c is between 130 and 150 kD under reducing conditions and 270 kD under non-reducing conditions. CD203c is expressed on basophils and mast cells, and is highly expressed on activated basophils. Secretory glands in endometrium and glioma cells are also positive. CD203c is a multifunctional ectoenzyme involved in the clearance of extracellular nucleotides whose substrates include nucleoside triphosphates, nucleoside diphosphates, cAMP, and NAD.