Purified Anti-Mouse TCR G Gamma/D Delta Antibody[GL3], Functional Grade

Size

£100.80

Was £112.00

SKU:: E-AB-F12820
Application:: Flow Cytometry
Concentration:: >= 1 mg/ml
Purification:: protein a/g purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Hamster
Reactivities:: Mouse
Buffer:: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Immunogen:: Recombinant Mouse TCR G Gamma/D Delta protein
Clone:: GL3
Extra Details:: T cell receptor (TCR) is a heterodimer consisting of an A Alpha and a B Beta chain (TCR A Alpha/B Beta) or a G Gamma and a D Delta chain (TCR G Gamma/D Delta). TCR G Gamma/D Delta belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. G Gamma/D Delta TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. T cells expressing the G Gamma/D Delta TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that G Gamma/D Delta T cells also play a principal role in antigen presentation. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.