E-AB-F12690
Purified Anti-Human CD86 Antibody[IT2.2], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F12690
- Additional Names:
- LAB,ETC,FUN,CTLA-4 Counter-Receptor B,Early T-cell costimulatory molecule,CD28LG,B7-2,B7.2,B70,CD28LG2,LAB72,CD86,Activation B7-2 antigen,BU63,CTLA-4 Counter-Receptor B7.2,Early T-cell costimulatory molecule 1,ETC-1,FUN-1,T-lymphocyte activation antigen CD86, B7-2,Activation B7-2 antigen 3,B7 2,B72 antigen,B-lymphocyte activation antigen B7-2,B-lymphocyte activation antigen B7-2 2,CD28 antigen ligand 2,CD28 antigen ligand 2 2,Cd28l2,CD86 antigen,CD86 molecule,CLS1,CTLA-4 counter-receptor B7.2
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Human CD86 protein
- Clone:
- IT2.2
- Uniprot:
- P42081
- Synonyms:
- Activation B7-2 antigen;B-lymphocyte activation antigen B7-2;B7-2;B7.2;B70;BU63;CD28LG2;CD86 antigen (CD28 antigen ligand 2, B7-2 antigen);CTLA-4 counter-receptor B7.2;FUN-1;LAB72;T-lymphocyte activation antigen CD86
- Extra Details:
- This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice