E-AB-F1235D
PE Anti-Mouse CD51 Antibody[RMV-7]
Size
£90.90
Was £101.00
- SKU:
- E-AB-F1235D
- Additional Names:
- ITGAV,Integrin alpha-V,Integrin A AlphaV chain,Vitronectin Receptor,A AlphaV integrin
- Application:
- Flow Cytometry
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- PBS
- Immunogen:
- CD51
- Clone:
- RMV-7
- Uniprot:
- P43406
- Synonyms:
- 1110004F14Rik;2610028E01Rik;alpha v integrin;CD51;D430040G12Rik;integrin alpha-V;vitronectin receptor alpha polypeptide (VNRA);vitronectin receptor subunit alpha
- Extra Details:
- CD51 is a 140 kD protein, also known as A AlphaV integrin, vitronectin receptor, and integrin A AlphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins B Beta1, B Beta3, B Beta5 or B Beta6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The A Alphavintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
- Shipping Conditions:
- Blue Ice