E-AB-F12350
Purified Anti-Mouse CD51 Antibody[RMV-7], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F12350
- Additional Names:
- Integrin alpha-V,Integrin A AlphaV chain,Vitronectin Receptor,A AlphaV integrin,Itgav,vitronectin R,integrin &,alpha-V-V
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rat
- Reactivities:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant MouseCD51 protein
- Clone:
- RMV-7
- Uniprot:
- P43406
- Synonyms:
- 1110004F14Rik;2610028E01Rik;alpha v integrin;CD51;D430040G12Rik;integrin alpha-V;vitronectin receptor alpha polypeptide (VNRA);vitronectin receptor subunit alpha
- Extra Details:
- CD51 is a 140 kD protein, also known as A AlphaV integrin, vitronectin receptor, and integrin A AlphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins B Beta1, B Beta3, B Beta5 or B Beta6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The A Alphav integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice