Purified Anti-Human CD80 Antibody[2D10], Functional Grade

Size

£80.10

Was £89.00

SKU:: E-AB-F12320
Additional Names:: LAB,CTLA-4 counter-receptor B,T-lymphocyte activation antigen CD,B7,B7-1,B7.1,BB1,CD28LG,CD28LG1,LAB7,CD80,CD28LGB7-1 antigen,T-lymphocyte activation antigen CD80,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1, B7-1, BB1,B lymphocyte activation antigen B7,B7-1 antigen,B7-1 antigen),CD28 antigen ligand 1,CD80 antigen,CD80 antigen (CD28 antigen ligand 1,CD80 molecule,Costimulatory factor CD80,costimulatory molecule variant IgV-CD80
Application:: Flow Cytometry
Concentration:: >= 1 mg/ml
Purification:: protein a/g purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Immunogen:: Recombinant Human CD80 protein
Clone:: 2D10
Uniprot:: P33681
Synonyms:: activation B7-1 antigen;B-lymphocyte activation antigen B7;B7;B7-1;B7.1;BB1;CD28LG;CD28LG1;CD80 antigen (CD28 antigen ligand 1, B7-1 antigen);costimulatory factor CD80;costimulatory molecule variant IgV-CD80;CTLA-4 counter-receptor B7.1;LAB7;T-lymphocyte activation antigen CD80
Extra Details:: B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.

Shipping Conditions:: Blue Ice