APC Anti-Rat CD44H Antibody[OX-49]

Size

£78.30

Was £87.00

SKU:: E-AB-F1225E
Additional Names:: CD44sH-CAM,CD44H,Pgp-1
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Rat
Buffer:: PBS
Immunogen:: CD44H
Clone:: OX-49
Uniprot:: P26051
Synonyms:: AU023126;AW121933;AW146109;CD44 antigen;CD44A;Cell surface glycoprotein CD44 (hyaluronate binding protein);ECMR-III;extracellular matrix receptor III;GP90 lymphocyte homing/adhesion receptor;HERM;HERMES;hermes antigen;HUTCH-I;hyaluronate receptor;Ly-2;Ly-24;lymphocyte antigen 24;METAA;Pgp;Pgp-1;PGP-I;phagocytic glycoprotein 1;phagocytic glycoprotein I;RHAMM
Extra Details:: CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.