E-AB-F12110
Purified Anti-Human CD11a Antibody[R7-1], Functional Grade
Size
£80.10
Was £89.00
- SKU:
- E-AB-F12110
- Additional Names:
- LFA,Lymphocyte antigen,CD11A,LFA-1,LFA1A,ITGAL,LFA-1A,Ly-15,Lymphocyte antigen 15,Integrin alpha-L,CD11 antigen-like family member A,Leukocyte adhesion glycoprotein LFA-1 alpha chain (LFA-1A),Leukocyte function-associated molecule 1 alpha chain, integrin &,alpha-L-L,LFA1
- Application:
- Flow Cytometry
- Concentration:
- >= 1 mg/ml
- Purification:
- protein a/g purified
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Human CD11A protein
- Clone:
- R7-1
- Uniprot:
- P20701
- Synonyms:
- antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide;CD11 antigen-like family member A;CD11A;integrin alpha-L;integrin gene promoter;integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide);leukocyte adhesion glycoprotein LFA-1 alpha chain;leukocyte function-associated molecule 1 alpha chain;LFA-1;LFA-1 alpha;LFA-1A;LFA1A;lymphocyte function-associated antigen 1, alpha polypeptide
- Extra Details:
- CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1A Alpha chain and integrin A AlphaL subunit. CD11a non-covalently associates with integrin B Beta2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Shipping Conditions:
- Blue Ice