E-AB-F1202E
APC Anti-Human IL-21 Antibody[3A3-N2]
Size
£128.70
Was £143.00
- SKU:
- E-AB-F1202E
- Additional Names:
- IL-21,Interleukin-21,Za11
- Application:
- Flow Cytometry
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- IL-21
- Clone:
- 3A3-N2
- Uniprot:
- Q9HBE4
- Synonyms:
- CVID11;IL-21;interleukin-21;Za11
- Extra Details:
- Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
- Shipping Conditions:
- Blue Ice