E-AB-F1195D
PE Anti-Human/Monkey CD28 Antibody[CD28.2]
Size
£82.80
Was £92.00
- SKU:
- E-AB-F1195D
- Additional Names:
- GPSAT,GYPA,HGpMiX,MNS,PAS2
- Application:
- Flow Cytometry
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS
- Immunogen:
- CD28
- Clone:
- CD28.2
- Uniprot:
- P10747
- Synonyms:
- T-cell-specific surface glycoprotein CD28;Tp44
- Extra Details:
- CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
- Shipping Conditions:
- Blue Ice