APC Anti-Mouse CD38 Antibody[NIMR5]

Size

£69.30

Was £77.00

SKU:: E-AB-F1193E
Additional Names:: 2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,CD38,NIM-R5 antigen
Application:: Flow Cytometry
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Elabscience
Host:: Rat
Reactivities:: Mouse
Buffer:: PBS
Immunogen:: CD38
Clone:: NIMR5
Uniprot:: P56528
Synonyms:: 2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADPRC 1;cADPr hydrolase 1;Cd38-r;Cd38-rs1;cyclic ADP-ribose hydrolase 1;I-19;NIM-R5 antigen
Extra Details:: CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.